EGLN1 Antikörper (AA 350-426)

Produktnummer ABIN540735

Produktdetails anti-EGLN1 Antikörper

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Bindungsspezifität: AA 350-426

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGLN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of EGLN1.

Spezifität: This antibody is specific to human HIF prolyl hydroxylase 2. There is 83 % homology between the immunogen used for this antibody and the rat and mouse proteins.

Kreuzreaktivität: Human

Immunogen: A synthetic peptide corresponding to amino acids 350-426 of human EGLN1.

Anwendungsinformationen

Applikationshinweise: The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Do not freeze.

Referenzen für anti-EGLN1 Antikörper (ABIN540735)

Wong, Goehring, Kapiloff, Langeberg, Scott: "mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha." in: Science signaling, Vol. 1, Issue 51, pp. ra18, (2008) (PubMed).

Colla, Tagliaferri, Morandi, Lunghi, Donofrio, Martorana, Mancini, Lazzaretti, Mazzera, Ravanetti, Bonomini, Ferrari, Miranda, Ladetto, Neri, Neri, Greco, Mangoni, Bonati, Rizzoli, Giuliani et al.: "The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha ..." in: Blood, Vol. 110, Issue 13, pp. 4464-75, (2007) (PubMed).

Ietta, Wu, Winter, Xu, Wang, Post, Caniggia: "Dynamic HIF1A regulation during human placental development." in: Biology of reproduction, Vol. 75, Issue 1, pp. 112-21, (2006) (PubMed).

Baek, Mahon, Oh, Kelly, Krishnamachary, Pearson, Chan, Giaccia, Semenza: "OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha." in: Molecular cell, Vol. 17, Issue 4, pp. 503-12, (2005) (PubMed).

Details zu EGLN1

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Andere Bezeichnung: EGLN1 / PHD2 (EGLN1 Produkte)

Synonyme: EGLN1 antikoerper, egln2 antikoerper, phd2 antikoerper, zgc:92314 antikoerper, AI503754 antikoerper, C1orf12 antikoerper, HIF-PH2 antikoerper, HPH-2 antikoerper, Hif-p4h-2 antikoerper, ORF13 antikoerper, Phd2 antikoerper, SM-20 antikoerper, PHD-2 antikoerper, PHD2 antikoerper, ECYT3 antikoerper, HIFPH2 antikoerper, HPH2 antikoerper, SM20 antikoerper, ZMYND6 antikoerper, egl nine homolog 1 (C. elegans) antikoerper, egl-9 family hypoxia inducible factor 1 antikoerper, egl-9 family hypoxia-inducible factor 1 S homeolog antikoerper, egl-9 family hypoxia-inducible factor 1b antikoerper, egl-9 family hypoxia-inducible factor 1 antikoerper, EGLN1 antikoerper, egln1.S antikoerper, egln1b antikoerper, Egln1 antikoerper

Gen-ID: 54583

Pathways: cAMP Metabolic Process, Warburg Effekt