LOX Antikörper (AA 200-300, AA 300-400)

Produktnummer ABIN540694

Produktdetails anti-LOX Antikörper

Target: LOX (Lysyl Oxidase (LOX))

Bindungsspezifität: AA 200-300, AA 300-400

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Schwein, Huhn, Rind (Kuh), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of LOX.

Kreuzreaktivität: Huhn, Rind (Kuh), Human, Maus, Schwein, Ratte, Xenopus laevis, Zebrafisch (Danio rerio)

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: A mixture of synthetic peptides corresponding to residues within 300-400 and 200-300 of human LOX.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
Western Blot (1:1000-1:5000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.02 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-LOX Antikörper (ABIN540694)

Osawa, Ohga, Akiyama, Hida, Kitayama, Kawamoto, Yamamoto, Maishi, Kondoh, Onodera, Fujie, Shinohara, Nonomura, Shindoh, Hida: "Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis." in: British journal of cancer, Vol. 109, Issue 8, pp. 2237-47, (2013) (PubMed).

Tanaka, Yamaguchi, Shoji, Nangaku: "Anthracycline inhibits recruitment of hypoxia-inducible transcription factors and suppresses tumor cell migration and cardiac angiogenic response in the host." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 34866-82, (2012) (PubMed).

Erler, Bennewith, Nicolau, Dornhöfer, Kong, Le, Chi, Jeffrey, Giaccia: "Lysyl oxidase is essential for hypoxia-induced metastasis." in: Nature, Vol. 440, Issue 7088, pp. 1222-6, (2006) (PubMed).

Thomassin, Werneck, Broekelmann, Gleyzal, Hornstra, Mecham, Sommer: "The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers." in: The Journal of biological chemistry, Vol. 280, Issue 52, pp. 42848-55, (2005) (PubMed).

Details zu LOX

Target: LOX (Lysyl Oxidase (LOX))

Andere Bezeichnung: Lysyl oxidase (LOX Produkte)

Synonyme: LOX antikoerper, Xlox antikoerper, MGC146507 antikoerper, lox antikoerper, zgc:77447 antikoerper, AI893619 antikoerper, TSC-160 antikoerper, H-rev142 antikoerper, Rrg1 antikoerper, lysyl oxidase antikoerper, lysyl oxidase a antikoerper, lysyl oxidase L homeolog antikoerper, LOX antikoerper, lox antikoerper, loxa antikoerper, lox.L antikoerper, Lox antikoerper

Gen-ID: 4015

Pathways: SARS-CoV-2 Protein Interaktom