LOX Produkte
(Lysyl Oxidase (LOX))
Kategorien
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
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Ausgewählte LOX Kategorien
LOX Antikörper
High quality antibodies with extensive validation data.
LOX ELISA Kits
Reliable ELISA kits for a wide range of species.
LOX Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene LOX Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC, IP
Validierungen
- (7)
Kat. Nr.
ABIN7435016
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Rat
Applikation
WB, IHC, FACS, IF, IHC (p)
Validierungen
- (7)
Kat. Nr.
ABIN1491218
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN6143288
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene LOX ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (8)
- (1)
Kat. Nr.
ABIN6957599
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6957600
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6957601
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LOX Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (12)
- (1)
Kat. Nr.
ABIN2712316
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123817
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3083215
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LOX Produkten
: "Eliminating Regurgitation Reduces Fibrotic Remodeling of Functional Mitral Regurgitation Conditioned Valves." in: Annals of biomedical engineering, Vol. 46, Issue 5, pp. 670-683, (2019) (PubMed).: "LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy." in: Oncogene, Vol. 37, Issue 36, pp. 4921-4940, (2019) (PubMed).
: "TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro." in: Connective tissue research, Vol. 60, Issue 5, pp. 495-506, (2019) (PubMed).
: "Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia." in: Experimental & molecular medicine, Vol. 51, Issue 2, pp. 20, (2019) (PubMed).
: "Lysyl oxidase-a possible role in systemic sclerosis-associated pulmonary hypertension: a multicentre study. ..." in: Rheumatology (Oxford, England), (2019) (PubMed).
: "LOX and ACSL5 as potential relapse markers for pancreatic cancer patients." in: Cancer biology & therapy, Vol. 20, Issue 6, pp. 787-798, (2019) (PubMed).
: "Decreased lysyl oxidase level protects against development of retinal vascular lesions in diabetic retinopathy." in: Experimental eye research, Vol. 184, pp. 221-226, (2019) (PubMed).
: "Cyclophilin B control of lysine post-translational modifications of skin type I collagen." in: PLoS genetics, Vol. 15, Issue 6, pp. e1008196, (2019) (PubMed).
: "Type III collagen is a key regulator of the collagen fibrillar structure and biomechanics of articular cartilage and meniscus." in: Matrix biology : journal of the International Society for Matrix Biology, (2019) (PubMed).
: "Lysyl Oxidase Is a Key Player in BRAF/MAPK Pathway-Driven Thyroid Cancer Aggressiveness." in: Thyroid : official journal of the American Thyroid Association, Vol. 29, Issue 1, pp. 79-92, (2019) (PubMed).
Synonyme und alternative Namen zu LOX
lysyl oxidase (LOX), lysyl oxidase (lox), lysyl oxidase a (loxa), lysyl oxidase L homeolog (lox.L), lysyl oxidase (Lox), AI893619, H-rev142, LOX, lox, MGC146507, Rrg1, TSC-160, Xlox, zgc:77447Bezeichner auf Proteinebene für LOX
- lysyl oxidase
- protein-lysine 6-oxidase-like
- protein-lysine 6-oxidase
- ras excision protein
- ras recision gene (rrg)
- Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts)
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