IL7R Antikörper (pTyr449)

Produktnummer ABIN538474

Produktdetails anti-IL7R Antikörper

Target: IL7R (Interleukin 7 Receptor (IL7R))

Bindungsspezifität: pTyr449

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL7R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of Il7r.

Spezifität: This antibody is specific to mouse IL-7 protein phosphorylated at Y449.

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Y449 of mouse Il7r.

Anwendungsinformationen

Applikationshinweise: ELISA (1:100000)
Western Blot (1:1000-1:10000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-IL7R Antikörper (ABIN538474)

Osborne, Dhanji, Snow, Priatel, Ma, Miners, Teh, Goldsmith, Abraham: "Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice." in: The Journal of experimental medicine, Vol. 204, Issue 3, pp. 619-31, (2007) (PubMed).

Hartigan-OConnor, Poon, Sinclair, McCune: "Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells." in: Journal of immunological methods, Vol. 319, Issue 1-2, pp. 41-52, (2007) (PubMed).

Castellino, Germain: "Chemokine-guided CD4+ T cell help enhances generation of IL-6RalphahighIL-7Ralpha high prememory CD8+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 2, pp. 778-87, (2007) (PubMed).

Details zu IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Andere Bezeichnung: CD127 / IL7R (IL7R Produkte)

Synonyme: IL7R antikoerper, CD127 antikoerper, IL-7Ralpha antikoerper, CDW127 antikoerper, IL-7R-alpha antikoerper, IL7RA antikoerper, ILRA antikoerper, IL-7RA antikoerper, interleukin 7 receptor antikoerper, IL7R antikoerper, Il7r antikoerper

Gen-ID: 16197

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size