XAF1
Reaktivität: Human
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
The optimal working dilution should be determined by the end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In PBS (0.05 % BSA, 0.05 % sodium azide)
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Straszewski-Chavez, Visintin, Karassina, Los, Liston, Halaban, Fadiel, Mor: "XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 13059-72, (2007) (PubMed).
Xia, Novak, Lewis, Duckett, Phillips: "Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP." in: Molecular and cellular biochemistry, Vol. 286, Issue 1-2, pp. 67-76, (2006) (PubMed).
Wang, Zhu, Wang, Hagberg, Korhonen, Sandberg, Lindholm, Blomgren: "X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia." in: Neurobiology of disease, Vol. 16, Issue 1, pp. 179-89, (2004) (PubMed).