FCGR3A Antikörper (PE)

Produktnummer ABIN535935

Produktdetails anti-FCGR3A Antikörper (PE)

Target: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FCGR3A Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP)

Verwendungszweck: Mouse monoclonal antibody raised against native FCGR3A.

Spezifität: This antibody reacts with CD16, a low affinity receptor for aggregated IgG (FcgammaRIII antigen). CD16 exists in two different isoforms: CD16a (FcgammaRIIIA, 50-65 KDa, expressed on NK-cells, monocytes and macrophages) and CD16b (FcgammaRIIIB, 48 KDa, mainly expressed on neutrophils).

Kreuzreaktivität: Human, Non-Human Primate

Immunogen: Native purified FCGR3A from normal human peripheral blood granulocytes.

Klon: LNK16

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-FCGR3A Antikörper (PE) (ABIN535935)

Boyle: "Human macrophages kill human mesangial cells by Fas-L-induced apoptosis when triggered by antibody via CD16." in: Clinical and experimental immunology, Vol. 137, Issue 3, pp. 529-37, (2004) (PubMed).

Arase, Arase, Hirano, Yokosuka, Sakurai, Saito: "IgE-mediated activation of NK cells through Fc gamma RIII." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 6, pp. 3054-8, (2003) (PubMed).

Details zu FCGR3A

Target: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Andere Bezeichnung: FCGR3A (FCGR3A Produkte)

Synonyme: CD16 antikoerper, CD16A antikoerper, FCG3 antikoerper, FCGR3 antikoerper, FCGRIII antikoerper, FCR-10 antikoerper, FCRIII antikoerper, FCRIIIA antikoerper, IGFR3 antikoerper, Fcgr4 antikoerper, Fc fragment of IgG receptor IIIa antikoerper, FCGR3A antikoerper, Fcgr3a antikoerper

Gen-ID: 2214