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Kinesin (heavy chain) Antikörper

Reaktivität: Schwein ICC, IF Wirt: Maus Monoclonal KN-02 unconjugated
Produktnummer ABIN535262
  • Target
    Kinesin (heavy chain)
    Reaktivität
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Schwein
    Wirt
    • 3
    Maus
    Klonalität
    • 3
    Monoklonal
    Konjugat
    • 3
    Unkonjugiert
    Applikation
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunocytochemistry (ICC), Immunofluorescence (IF)
    Verwendungszweck
    Mouse monoclonal antibody raised against native Kinesin (heavy chain).
    Spezifität
    This antibody recognizes heavy chain of conventional kinesin associated withvesicles and with lower affinity with denaturated molecule. Epitope is located in coiled-coilstalk domain. It stains Western blots of kinesin-enriched preparations. Epitope mapping (by limited proteolysis of partially purified porcine kinesin) followed by immunoblotting has revealed that antibodies MAB3620, MAB3621 and MAB3622 react with differentsets of fragments. This antibody does not react with kinesin bound to taxol-stabilized microtubules.
    Kreuzreaktivität
    Human, Maus, Schwein, Ratte
    Immunogen
    Native purified porcine Kinesin (heavy chain).
    Klon
    KN-02
    Isotyp
    IgM
  • Applikationshinweise
    The optimal working dilution should be determined by the end user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    In PBS, pH 7.4 (0.09 % sodium azide)
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 4°C. Do not freeze.
  • Malcová-Janatová, Richterová, Dráber, Hasek: "Preparation of human recombinant kinesin heavy chain and epitope mapping of its structural domains." in: Folia microbiologica, Vol. 49, Issue 6, pp. 665-70, (2005) (PubMed).

    Mac?rek, Dráberová, Richterová, Böhm, Dráber: "Monoclonal antibodies KN-02 and KN-03 against the heavy chain of kinesin." in: Hybridoma and hybridomics, Vol. 21, Issue 6, pp. 457-62, (2003) (PubMed).

  • Target
    Kinesin (heavy chain)
    Synonyme
    KINH antikoerper, KNS antikoerper, KNS1 antikoerper, UKHC antikoerper, kinesin family member 5B antikoerper, kinesin family member 5C antikoerper, KIF5B antikoerper, Kif5c antikoerper
    Pathways
    Peptide Hormone Metabolism
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