USP7 Antikörper (AA 932-1100)

Produktnummer ABIN5027626

Produktdetails anti-USP7 Antikörper

Target: USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

Bindungsspezifität: AA 932-1100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant USP7 protein (amino acids 932-1100) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu USP7

Target: USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

Andere Bezeichnung: USP7 (USP7 Produkte)

Synonyme: CG1490 antikoerper, Dmel\\CG1490 antikoerper, USP7 antikoerper, 2210010O09Rik antikoerper, AA409944 antikoerper, AA617399 antikoerper, AU019296 antikoerper, AW548146 antikoerper, C80752 antikoerper, Hausp antikoerper, HAUSP antikoerper, TEF1 antikoerper, UBP antikoerper, Ubiquitin-specific protease 7 antikoerper, ubiquitin carboxyl-terminal hydrolase 7 antikoerper, ubiquitin specific peptidase 7 antikoerper, Usp7 antikoerper, LOC100201254 antikoerper, USP7 antikoerper

Hintergrund: USP7 (ubiquitin specific peptidase 7) is a deubiquitinating enzyme that prevents protein degradation by removing poly-ubiquitin chains from its substrates. It regulates stability of a number of human transcription factors and tumor suppressors and plays a critical role in the development of several types of cancer, including prostate and small cell lung cancer.USP7 regulates Pol-eta (DNA polymerase eta) stability through both indirect and direct mechanisms. It regulates the stability of the DNA maintenance methyltransferase. Diseases associated with USP7 include UV-sensitive syndrome.

Molekulargewicht: 120 kDa

Gen-ID: 7874

UniProt: Q93009