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RUNX2 Antikörper (AA 161-482)
RUNX2
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5027510
Produktdetails anti-RUNX2 Antikörper
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Target
Alle RUNX2 Antikörper anzeigen
RUNX2
(Runt-Related Transcription Factor 2 (RUNX2))
Bindungsspezifität
Alle Epitope für RUNX2 Antikörper
AA 161-482
Reaktivität
Alle Reaktivitäten für RUNX2 Antikörper
Human
Wirt
Alle Wirte für RUNX2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für RUNX2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für RUNX2 Antikörper
Dieser RUNX2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für RUNX2 Antikörper
Western Blotting (WB)
Aufreinigung
Protein A Chromatography
Immunogen
A partial length recombinant RUNX2 protein (amino acids 161-482) was used as the immunogen for this antibody.
Isotyp
IgG
Top Product
Discover our top product RUNX2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB: 1-3 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Details zu RUNX2
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Target
RUNX2
(Runt-Related Transcription Factor 2 (RUNX2))
Andere Bezeichnung
RUNX2 (RUNX2 Produkte )
Synonyme
AML3 antikoerper, CBF-alpha-1 antikoerper, CBFA1 antikoerper, CCD antikoerper, CCD1 antikoerper, CLCD antikoerper, OSF-2 antikoerper, OSF2 antikoerper, PEA2aA antikoerper, PEBP2aA antikoerper, Cbf antikoerper, Cbfa-1 antikoerper, Cbfa1 antikoerper, LS3 antikoerper, Osf2 antikoerper, Pebp2a1 antikoerper, Pebpa2a antikoerper, runx2 antikoerper, RUNX2 antikoerper, ccd antikoerper, aml3 antikoerper, ccd1 antikoerper, osf2 antikoerper, cbfa1 antikoerper, pea2aa antikoerper, pebp2a1 antikoerper, pebp2a2 antikoerper, pebp2aa antikoerper, pebp2aa1 antikoerper, runt related transcription factor 2 antikoerper, runt-related transcription factor 2a antikoerper, runt-related transcription factor 2 antikoerper, runt related transcription factor 2 L homeolog antikoerper, RUNX2 antikoerper, runx2a antikoerper, Runx2 antikoerper, runx2 antikoerper, LOC703331 antikoerper, LOC100549663 antikoerper, runx2.L antikoerper
Hintergrund
Runt-related transcription factor 2 (Runx2) is also known as core-binding factor subunit alpha-1 (CBF-alpha-1). RunX2 is one of the three mammalian transcription factors sharing the highly conserved DNA-binding Runt domain that represents a key class of lineage-specific gene regulators and is associated with different micro-environments during the cell cycle. RUNX2 has a primary role in the differentiation of osteoblasts and hypertrophy of cartilage at the growth plate, cell migration and vascular invasion of bone and is also expressed in vascular endothelial cells and breast cancer cells. It is a heterodimer of an alpha and a beta subunit. RUNX2 plays a role in the disease metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly, and cleidocranial dysplasia. By alternative splicing, several isoforms exist.
Molekulargewicht
50 kDa
Gen-ID
860
UniProt
Q13950
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