IL1RL2 Antikörper (AA 1-203)

Produktnummer ABIN5027305

Produktdetails anti-IL1RL2 Antikörper

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Bindungsspezifität: AA 1-203

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL1RL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant IL-36R protein (amino acids 1-203) was used as the immunogen for this antibody.

Klon: ABM4B73

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu IL1RL2

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Andere Bezeichnung: IL-36R (IL1RL2 Produkte)

Synonyme: IL-1Rrp2 antikoerper, IL-36R antikoerper, IL1R-rp2 antikoerper, IL1RRP2 antikoerper, AI481289 antikoerper, AW551444 antikoerper, interleukin 1 receptor like 2 antikoerper, interleukin 1 receptor-like 2 antikoerper, IL1RL2 antikoerper, Il1rl2 antikoerper

Hintergrund: IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The latter is also used by IL-1Alpha and IL-1 Beta. IL-36R is expressed by different immune cells, including Dendritic Cells, microglia and other myeloid cells. IL-36 stimulation of DC leads to the production of several cytokines by DC, including TNF-a, IL-1, IL-12, and IL-23. This interaction also enhances the expression of MHC class 2 and co-stimulatory molecules.

Molekulargewicht: 69 kDa

Gen-ID: 8808

UniProt: Q9HB29