IL1RL2 Antikörper (C-Term)
Kurzübersicht für IL1RL2 Antikörper (C-Term) (ABIN358951)
Target
Alle IL1RL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody reacts to IL1R.
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Aufreinigung
- Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal(E487) region of human IL1R.
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Isotyp
- Ig Fraction
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Applikationshinweise
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ELISA: 1/1,000 . Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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: "GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response." in: Scientific reports, Vol. 6, pp. 24354, (2017) (PubMed).
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- IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))
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Andere Bezeichnung
- IL1RL2 / IL1RRP2
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Hintergrund
- IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.Synonyms: IL-1Rrp2, Interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2
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Gen-ID
- 8808, 9606
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UniProt
- Q9HB29
Target
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