C-Type Lectin Domain Family 6, Member A (CLEC6A) (AA 70-230) Antikörper

Produktnummer ABIN5027146

Produktdetails

Target: C-Type Lectin Domain Family 6, Member A (CLEC6A)

Bindungsspezifität: AA 70-230

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Kreuzreaktivität: Maus

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant Dectin-2 protein (amino acids 70-230) was used as the immunogen for this antibody.

Klon: ABM2H28

Isotyp: IgG3 kappa

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL,FACS: 0.5 μg/10^6 cells, IHC: 5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: C-Type Lectin Domain Family 6, Member A (CLEC6A)

Andere Bezeichnung: Dectin-2 (CLEC6A Produkte)

Synonyme: CLEC4N antikoerper, CLECSF10 antikoerper, CLEC6A antikoerper, C-type lectin domain containing 6A antikoerper, C-type lectin domain family 6, member A antikoerper, CLEC6A antikoerper, Clec6a antikoerper

Hintergrund: Dectin-2 (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. Dectin-2 plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. It binds high-mannose carbohydrates in a Ca(2+)-dependent manner. In Dectin-2 glycosylation occurs at Asn131, Asn170. Dectin-2 has 2 isoforms produced by alternative splicing. Dectin-2 is strongly expressed in monocytes and weakly in B-cells and also expressed in spleen, tonsils, lymph node, lungs, leukocytes, dendritic cells and bone marrow.

Molekulargewicht: 32 kDa

Gen-ID: 93978

UniProt: Q6EIG7