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C-Type Lectin Domain Family 6, Member A Produkte

(C-Type Lectin Domain Family 6, Member A (CLEC6A))
Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functionnal receptor for alpha-mannans on C. albicans hypheas. Plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. Recognizes also, in a manose dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptative immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway.

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Ausgewählte C-Type Lectin Domain Family 6, Member A Kategorien

C-Type Lectin Domain Family 6, Member A Antikörper

High quality antibodies with extensive validation data.

C-Type Lectin Domain Family 6, Member A ELISA Kits

Reliable ELISA kits for a wide range of species.

C-Type Lectin Domain Family 6, Member A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene C-Type Lectin Domain Family 6, Member A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7186528
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, FACS, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN959984
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, ICC
Validierungen
  • (2)
Kat. Nr. ABIN6260891
Menge 100 μL
Datenblatt Datenblatt

Empfohlene C-Type Lectin Domain Family 6, Member A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6730425
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4882590
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6385418
Menge 96 tests
Datenblatt Datenblatt

Empfohlene C-Type Lectin Domain Family 6, Member A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7320341
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3077834
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3130235
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren C-Type Lectin Domain Family 6, Member A Produkten

Botting, Bertram, Baharlou, Sandgren, Fletcher, Rhodes, Rana, Plasto, Wang, Lim, Barnouti, Kohout, Papadopoulos, Merten, Olbourne, Cunningham, Haniffa, Harman: "Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes." in: Journal of leukocyte biology, Vol. 101, Issue 6, pp. 1393-1403, (2017) (PubMed).

Brasch, Mörig, Neumann, Proksch: "Expression of antimicrobial peptides and toll-like receptors is increased in tinea and pityriasis versicolor." in: Mycoses, Vol. 57, Issue 3, pp. 147-52, (2014) (PubMed).

Barrett, Rahman, Fernandez, Parsons, Xing, Austen, Kanaoka: "Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes." in: The Journal of experimental medicine, Vol. 208, Issue 3, pp. 593-604, (2011) (PubMed).

Gringhuis, Wevers, Kaptein, van Capel, Theelen, Boekhout, de Jong, Geijtenbeek: "Selective C-Rel activation via Malt1 controls anti-fungal T(H)-17 immunity by dectin-1 and dectin-2." in: PLoS pathogens, Vol. 7, Issue 1, pp. e1001259, (2011) (PubMed).

Suram, Gangelhoff, Taylor, Rosas, Brown, Bonventre, Akira, Uematsu, Williams, Murphy, Leslie: "Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30676-85, (2010) (PubMed).

Taylor, Reid, Heinsbroek, Brown, Gordon, Wong: "Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo." in: European journal of immunology, Vol. 35, Issue 7, pp. 2163-74, (2005) (PubMed).

Synonyme und alternative Namen zu C-Type Lectin Domain Family 6, Member A

C-type lectin domain containing 6A (CLEC6A), C-type lectin domain family 6, member A (Clec6a), CLEC4N, CLEC6A, CLECSF10

Bezeichner auf Proteinebene für C-Type Lectin Domain Family 6, Member A

  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10
  • C-type lectin domain family 6 member A
  • C-type lectin superfamily member 10
  • DC-associated C-type lectin 2
  • dectin 2
  • dectin-2
  • dendritic cell-associated C-type lectin 2
  • C-type lectin domain family 6, member A
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