CRHR2 Antikörper (AA 1-200)

Produktnummer ABIN5027120

Produktdetails anti-CRHR2 Antikörper

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Bindungsspezifität: AA 1-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRHR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant CRHR2 protein (amino acids 1-200) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 0.5-2.0 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu CRHR2

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Andere Bezeichnung: CRHR2 (CRHR2 Produkte)

Synonyme: CRF-RB antikoerper, CRF2 antikoerper, CRFR2 antikoerper, HM-CRF antikoerper, CRF-R2 antikoerper, CRFR2alpha antikoerper, CRFR2beta antikoerper, Crfr2 antikoerper, Crf2r antikoerper, CRH-R2 antikoerper, crhr2-A antikoerper, corticotropin releasing hormone receptor 2 antikoerper, corticotropin releasing hormone receptor 2 S homeolog antikoerper, CRHR2 antikoerper, Crhr2 antikoerper, crhr2.S antikoerper

Hintergrund: CRHR2 (CRF2R, CRH2R) (corticotropin releasing hormone receptor 2) belongs to the G-protein coupled receptor 2 family. This receptor has high affinity for corticotropin releasing hormone (CRH) and may also bind to CRH-related peptides, such as, urocortin. The human CRHR2 gene contains 12 exons. Three major functional isoforms have been reported: alpha, beta and gamma encoded by transcripts with alternative first exons which differ from each other by signal sequence and extra-cellular domain. CRH is synthesized in the hypothalamus and plays an important role in coordinating the endocrine, autonomic and behavioral responses to stress and immune challenge. CRHR2 has high expression in brain, caudate nucleus, cerebrum, colon, endometrium, etc.

Molekulargewicht: 46 kDa

Gen-ID: 1395

UniProt: Q13324

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour