ASAP1 Antikörper (AA 912-1115)

Produktnummer ABIN5027041

Produktdetails anti-ASAP1 Antikörper

Target: ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))

Bindungsspezifität: AA 912-1115

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant ASAP1 protein (amino acids 912-1115) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu ASAP1

Target: ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))

Andere Bezeichnung: ASAP1 (ASAP1 Produkte)

Synonyme: AV239055 antikoerper, DEF-1 antikoerper, Ddef1 antikoerper, PAP antikoerper, mKIAA1249 antikoerper, s19 antikoerper, AMAP1 antikoerper, CENTB4 antikoerper, DDEF1 antikoerper, PAG2 antikoerper, ZG14P antikoerper, ASAP1 antikoerper, ddef1 antikoerper, Asap1 antikoerper, si:ch211-160i2.3 antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain1 antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 antikoerper, toxic extracellular endopeptidase antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a antikoerper, Asap1 antikoerper, ASAP1 antikoerper, asaP1 antikoerper, asap1 antikoerper, asap1.L antikoerper, asap1a antikoerper

Hintergrund: ASAP (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1) or Development and differentiation-enhancing factor 1 or DDEF1 is an ADP-ribosylation factor (ARF) GTPase-activating protein with two known isoforms: ASAP1a and ASAP1b (125 and 126 kDa, respectively). ASAP contains a pleckstrin homology (PH) domain, a zinc finger motif, 3 ankyrin repeats, a proline-rich region containing several SH3 ligand motifs, and an SH3 domain. GTPase-activating property of ASAP1 is induced by phosphatidylinositol 4,5-biphosphate (PIP2) of the PH domain. ASAP1 plays an important role in cytoskeleton remodeling and regulation of membrane trafficking. ASAP1 acts as a proto-oncogene in breast cancer and other malignant tumors. ASAP is highly expressed in brain tissue.

Molekulargewicht: 115 kDa

Gen-ID: 13196

UniProt: Q9QWY8