S100A8 Antikörper
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- Target Alle S100A8 Antikörper anzeigen
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser S100A8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Protein G Chromatography
- Immunogen
- A full length human S100A8 protein was used as the immunogen for this antibody.
- Klon
- ABM4G30
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product S100A8 Primärantikörper
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- Applikationshinweise
- WB: 2-4 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
- Andere Bezeichnung
- S100A8 (S100A8 Produkte)
- Synonyme
- 60B8AG antikoerper, CAGA antikoerper, CFAG antikoerper, CGLA antikoerper, CP-10 antikoerper, L1Ag antikoerper, MA387 antikoerper, MIF antikoerper, MRP8 antikoerper, NIF antikoerper, P8 antikoerper, Mrp8 antikoerper, S100A8 antikoerper, 60B8Ag antikoerper, AI323541 antikoerper, B8Ag antikoerper, CFAg antikoerper, Caga antikoerper, p8 antikoerper, MRP-8 antikoerper, S100 calcium binding protein A8 antikoerper, S100 calcium binding protein A8 (calgranulin A) antikoerper, S100A8 antikoerper, S100a8 antikoerper
- Hintergrund
- S100A8 is a low molecular weight (10 kDa) secreted cytoplasmic protein belonging to S100 family of calcium- and zinc-binding protein. S100A8 regulates a number of cellular processes, such as, inflammation, antimicrobial, oxidant-scavenging and apoptosis-inducing activities, cell cycle progression and differentiation, leukocyte arachidonic acid trafficking and metabolism. S100A8 is a homodimer but predominantly remains as heterodimer with S100A9 and the S100A8/S100A9 complex is called as Calprotectin. S100A8 is generally expressed in myeloid cells, neutrophils, monocytes and keratinocytes but high levels are found in the serum sample of patients with inflammatory diseases, such as, rheumatoid, cystic fibrosis, inflammatory bowel disease, systemic lupus erythematosus, progressive systemic sclerosis and many other inflammatory diseases. S100A8 is also associated with Psoriasis (an inflammatory skin disorder characterized by keratinocyte hyperproliferation and altered differentiation).
- Molekulargewicht
- 10 kDa
- Gen-ID
- 6279
- UniProt
- P05109
- Pathways
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteine
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