TNIK Antikörper (AA 1281-1360) (Alexa Fluor 750)

Produktnummer ABIN5011784

Produktdetails anti-TNIK Antikörper (Alexa Fluor 750)

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Bindungsspezifität: AA 1281-1360

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNIK Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNIK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TNIK

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Andere Bezeichnung: TNIK (TNIK Produkte)

Synonyme: RGD1561817 antikoerper, TNIK antikoerper, 1500031A17Rik antikoerper, 4831440I19Rik antikoerper, AI451411 antikoerper, C530008O15Rik antikoerper, C630040K21Rik antikoerper, fc52d11 antikoerper, msn antikoerper, tnikl antikoerper, wu:fc52d11 antikoerper, zgc:63535 antikoerper, im:6898857 antikoerper, zgc:123033 antikoerper, zgc:152783 antikoerper, tnik antikoerper, TRAF2 and NCK interacting kinase antikoerper, TRAF2 and NCK interacting kinase a antikoerper, TRAF2 and NCK interacting kinase b antikoerper, TRAF2 and NCK interacting kinase S homeolog antikoerper, TNIK antikoerper, Tnik antikoerper, tnika antikoerper, tnikb antikoerper, tnik.S antikoerper

Hintergrund:

Synonyms: Traf2 and NCK interacting kinase, 1500031A17RIK, 4831440I19RIK, AI451411, C530008O15Rik, C630040K21RIK, KIAA0551, MGC189819, MGC189859, RGD1561817, TNIK, TNIK_HUMAN, TRAF2 and NCK-interacting protein kinase.

Background: TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when over expressed in Phoenix-A cells. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. Northern analysis indicates TNIK expression in human heart, skeletal muscle, and brain, with lower levels of expression in kidney, liver, lung, and pancreas. ESTs have been isolated from human tissue libraries, including normal amnion, gallbladder and skin.

Gen-ID: 23043