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TNIK Antikörper (pSer764)

TNIK Reaktivität: Maus, Ratte ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN711941
  • Target Alle TNIK Antikörper anzeigen
    TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
    Bindungsspezifität
    • 23
    • 15
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer764
    Reaktivität
    • 78
    • 55
    • 37
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 104
    • 4
    Kaninchen
    Klonalität
    • 104
    • 4
    Polyklonal
    Konjugat
    • 40
    • 10
    • 9
    • 9
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TNIK Antikörper ist unkonjugiert
    Applikation
    • 50
    • 44
    • 28
    • 26
    • 26
    • 19
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    Phosphorylation site corresponds to Ser735 in mouse
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764
    Isotyp
    IgG
    Top Product
    Discover our top product TNIK Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
    Andere Bezeichnung
    TNIK (TNIK Produkte)
    Synonyme
    RGD1561817 antikoerper, TNIK antikoerper, 1500031A17Rik antikoerper, 4831440I19Rik antikoerper, AI451411 antikoerper, C530008O15Rik antikoerper, C630040K21Rik antikoerper, fc52d11 antikoerper, msn antikoerper, tnikl antikoerper, wu:fc52d11 antikoerper, zgc:63535 antikoerper, im:6898857 antikoerper, zgc:123033 antikoerper, zgc:152783 antikoerper, tnik antikoerper, TRAF2 and NCK interacting kinase antikoerper, TRAF2 and NCK interacting kinase a antikoerper, TRAF2 and NCK interacting kinase b antikoerper, TRAF2 and NCK interacting kinase S homeolog antikoerper, TNIK antikoerper, Tnik antikoerper, tnika antikoerper, tnikb antikoerper, tnik.S antikoerper
    Hintergrund

    Synonyms: TRAF2 and NCK-interacting protein kinase, TNIK, KIAA0551

    Background: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.

    Gen-ID
    23043
    UniProt
    Q9UKE5
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