SMARCD3 Antikörper (Alexa Fluor 750)

Produktnummer ABIN5010744

Produktdetails anti-SMARCD3 Antikörper (Alexa Fluor 750)

Target: SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMARCD3 Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SMARCD3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SMARCD3

Target: SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))

Andere Bezeichnung: SMARCD3 (SMARCD3 Produkte)

Synonyme: SMARCD3 antikoerper, baf60c antikoerper, cracd3 antikoerper, rsc6p antikoerper, BAF60C antikoerper, CRACD3 antikoerper, Rsc6p antikoerper, 1500001J14Rik antikoerper, 2210409C08Rik antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 S homeolog antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b antikoerper, SMARCD3 antikoerper, smarcd3.S antikoerper, Smarcd3 antikoerper, smarcd3b antikoerper

Hintergrund:

Synonyms: 60 kDa BRG 1/Brm associated factor subunit C, 60 kDa BRG-1/Brm-associated factor subunit C, BAF60C, BRG1 associated factor 60C, BRG1-associated factor 60C, CRACD3, MGC111010, Rsc6p, Smarcd3, SMRD3_HUMAN, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily d member 3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3.

Background: SMARCD3, is a member of the SMARCD family and contains one SWIB domain. Two isoforms, isoform 1 and isoform 2 exist due to alternative splicing events. Both isoforms are expressed in placenta, salivary gland, kidney, brain, trachea, uterus, prostate, testis, thyroid, spleen and heart, while isoform 1 is also expressed in adipose tissue and skeletal muscle. Localizing to the nucleus, SMARCD3 is a component of the ATP-dependent chromatin remodeling complex SNF/SWI and is believed to play a role in nucleosome remodeling. SMARCD3 also plays an important role in the regulation of muscle development. In mice, the silencing of the gene en-coding SMARCD3 leads to defects in heart morphogenesis. In addition, both isoforms of SMARCD3 directly interact with and function as coactivators for several transcription factors.

Gen-ID: 6604

Pathways: Regulation of Lipid Metabolism by PPARalpha