SMARCD3 Antikörper (N-Term)
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- Target Alle SMARCD3 Antikörper anzeigen
- SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))
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Bindungsspezifität
- AA 27-60, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMARCD3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Homologie
- M
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SMARCD3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-60 amino acids from the N-terminal region of human SMARCD3.
- Klon
- RB48016
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SMARCD3 Primärantikörper
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- Applikationshinweise
- IF: 1:25. WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))
- Andere Bezeichnung
- SMARCD3 (SMARCD3 Produkte)
- Synonyme
- SMARCD3 antikoerper, baf60c antikoerper, cracd3 antikoerper, rsc6p antikoerper, BAF60C antikoerper, CRACD3 antikoerper, Rsc6p antikoerper, 1500001J14Rik antikoerper, 2210409C08Rik antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 S homeolog antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b antikoerper, SMARCD3 antikoerper, smarcd3.S antikoerper, Smarcd3 antikoerper, smarcd3b antikoerper
- Hintergrund
- Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron- specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
- Molekulargewicht
- 55016
- UniProt
- Q6STE5
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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