DOCK1 Antikörper (AA 465-550) (Alexa Fluor 750)

Produktnummer ABIN5001421

Produktdetails anti-DOCK1 Antikörper (Alexa Fluor 750)

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Bindungsspezifität: AA 465-550

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK1 Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DOCK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DOCK1

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Andere Bezeichnung: DOCK1 (DOCK1 Produkte)

Synonyme: DOCK180 antikoerper, ced5 antikoerper, 9130006G06Rik antikoerper, AI854900 antikoerper, D630004B07Rik antikoerper, RGD1566072 antikoerper, dedicator of cytokinesis 1 antikoerper, dedicator of cytokinesis protein 1 antikoerper, dedicator of cyto-kinesis 1 antikoerper, DOCK1 antikoerper, Dock1 antikoerper, dock1 antikoerper, CpipJ_CPIJ002759 antikoerper

Hintergrund:

Synonyms: 180 kDa protein downstream of CRK, Ced5, Dedicator of Cytokinesis 1, Dedicator of cytokinesis protein 1, DOCK 1, DOCK-1, DOCK 180, DOCK1, DOCK1_HUMAN, DOCK180.

Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.

Gen-ID: 1793

Pathways: Signaling of Hepatocyte Growth Factor Receptor