ADAR Antikörper (AA 1001-1226) (Alexa Fluor 750)

Produktnummer ABIN4996090

Produktdetails anti-ADAR Antikörper (Alexa Fluor 750)

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Bindungsspezifität: AA 1001-1226

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAR Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADAR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ADAR

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Andere Bezeichnung: ADAR1 (ADAR Produkte)

Synonyme: red1 antikoerper, drada antikoerper, wu:fc22a02 antikoerper, adar1 antikoerper, dsRAD antikoerper, dsRAD-1 antikoerper, ADAR antikoerper, ADAR1 antikoerper, CG12598 antikoerper, Dmel\\CG12598 antikoerper, EG:BACN35H14.1 antikoerper, adar antikoerper, adr antikoerper, cg12598 antikoerper, dADAR antikoerper, dAdar antikoerper, hypnos-2 antikoerper, NV18763 antikoerper, AGS6 antikoerper, DRADA antikoerper, DSH antikoerper, DSRAD antikoerper, G1P1 antikoerper, IFI-4 antikoerper, IFI4 antikoerper, K88DSRBP antikoerper, P136 antikoerper, AV242451 antikoerper, Adar1 antikoerper, mZaADAR antikoerper, adenosine deaminase, RNA-specific antikoerper, adenosine deaminase, RNA-specific S homeolog antikoerper, adenosine deaminase, RNA specific antikoerper, Adenosine deaminase acting on RNA antikoerper, adenosine deaminase acting on RNA antikoerper, double-stranded RNA-specific editase 1 antikoerper, adar antikoerper, adar.S antikoerper, ADAR antikoerper, Adar antikoerper, CpipJ_CPIJ011849 antikoerper, LOC100114127 antikoerper

Hintergrund:

Synonyms: 136 kDa double stranded RNA binding protein, Adar 1, ADAR, Adar1, Adenosine deaminase RNA specic 1, Adenosine deaminase RNA specic, Adenosine deaminase that act on RNA, AV242451, Double stranded RNA specic adenosine deaminase, Double-stranded RNA-specic editase Adar, Drada, Dsh, Dsrad, dsRNA adenosine deaminase, EC 3.5.4.-, G1P1, I 4, I4, i4 protein, Interferon induced protein 4, Interferon inducible protein 4, K88dsrbp, mZaADAR, p136, Pre-mRNA adenosine deaminase, RNA adenosine deaminase 1, RNA-editing deaminase 1, RNA-editing enzyme 1.

Background: ADAR1 converts adenosine to inosine in dsRNA, which destabilizes the dsRNA helix. This activity is important for various functions like site-specific RNA editing of transcripts of the glutamate receptors and modifying viral RNA genomes (which may be responsible for hypermutation of certain negative-stranded viruses, e.g., measles virus). ADAR1 also binds to short interfering RNAs (siRNA) without editing them and suppresses siRNA-mediated RNA interference. This protein is ubiquitously expressed, with the highest levels being found in brain and lung.

Gen-ID: 103

Pathways: Protein targeting to Nucleus