BCMA Antikörper

Produktnummer ABIN499437

Produktdetails anti-BCMA Antikörper

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCMA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: BCMA antibody was raised against a synthetic peptide mapping at the carboxy terminus of human BCMA.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human BCMA Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: BCMA antibody can be used for detection of BCMA at 2 to 5 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu BCMA

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Andere Bezeichnung: CD269 / BCMA (TNFRSF17 Produkte)

Synonyme: TNFRSF17 antikoerper, BCM antikoerper, BCMA antikoerper, CD269 antikoerper, TNFRSF13A antikoerper, Tnfrsf13 antikoerper, Tnfrsf13a antikoerper, TNF receptor superfamily member 17 antikoerper, tumor necrosis factor receptor superfamily, member 17 antikoerper, Tnfrsf17 antikoerper, TNFRSF17 antikoerper

Hintergrund: Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 (1-4) and April/TALL-2, respectively, (3,5). BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified (6,7). BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.Synonyms: B-cell maturation protein, BCM, TNFRSF17, Tumor necrosis factor receptor superfamily member 17

Gen-ID: 608

NCBI Accession: NP_001183

UniProt: Q02223