Activin A Receptor Type IB/ALK-4 Antikörper (C-Term)

Produktnummer ABIN499207

Produktdetails anti-Activin A Receptor Type IB/ALK-4 Antikörper

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Activin A Receptor Type IB/ALK-4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to ACVR1B near the carboxy terminus.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: ACVR1B antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human ACVR1B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: ACVR1B antibody can be used for detection of ACVR1B at 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Activin A Receptor Type IB/ALK-4

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Andere Bezeichnung: Activin Receptor Type 1B (ACVR1B) (ACVR1B Produkte)

Synonyme: ACVR1B antikoerper, alk4 antikoerper, skr2 antikoerper, alk-4 antikoerper, xalk4 antikoerper, actrib antikoerper, acvrlk4 antikoerper, DKFZp469A1614 antikoerper, 6820432J04 antikoerper, ActR-IB antikoerper, ActRIB antikoerper, Acvrlk4 antikoerper, Alk4 antikoerper, SKR2 antikoerper, ACTRIB antikoerper, ACVRLK4 antikoerper, ALK4 antikoerper, Skr2 antikoerper, axis antikoerper, taram-a antikoerper, tarama antikoerper, wu:fb75f01 antikoerper, activin A receptor type 1B antikoerper, Activin receptor type-1B antikoerper, activin A receptor, type IB antikoerper, activin A receptor, type 1B antikoerper, activin A receptor type 1Ba antikoerper, ACVR1B antikoerper, acvr1b antikoerper, acv1b antikoerper, Acvr1b antikoerper, acvr1ba antikoerper

Hintergrund: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. ACVR1B, also known as activin receptor-like kinase 4 (ALK4), is a type I receptor for activin and plays major roles in cell differentiation, growth arrest and apoptosis. Like another type I activin receptor ACVR1C, ACVR1B can mediate signaling by ligands such as Nodal, Xnr1, GDF-1/3, activin B and activin AB. In Xenopus embryos, expression of a dominant-negative form of ACVR1B blocked all mesoderm-inducing ligands, while expression of a dominant negative ACVR1C only blocked Nodal and Xnr1 signaling, suggesting that the ACVR1B and ACVR1C possess distinct functions. At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.Synonyms: ACTR-IB, ACVRLK4, ALK4, Activin receptor type IB, Activin receptor-like kinase 4, SKR2, Serine/threonine-protein kinase receptor R2

Gen-ID: 91

NCBI Accession: NP_004293

UniProt: P36896