CDC42EP2 Antikörper

Produktnummer ABIN499043

Produktdetails anti-CDC42EP2 Antikörper

Target: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC42EP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of Cdc42EP2 protein. (region surrounding Leu24)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CDC42EP2

Target: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Andere Bezeichnung: CDC42EP2 (CDC42EP2 Produkte)

Synonyme: CDC42EP2 antikoerper, zgc:103557 antikoerper, BORG1 antikoerper, CEP2 antikoerper, 1110008C05Rik antikoerper, Borg1 antikoerper, Cep2 antikoerper, D19Bwg1013e antikoerper, CDC42 effector protein 2 antikoerper, CDC42 effector protein 2 S homeolog antikoerper, CDC42 effector protein (Rho GTPase binding) 2 antikoerper, CDC42EP2 antikoerper, cdc42ep2.S antikoerper, cdc42ep2 antikoerper, Cdc42ep2 antikoerper

Hintergrund: Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.Synonyms: BORG1, Binder of Rho GTPases 1, CEP2, Cdc42 effector protein 2

Molekulargewicht: approx. 30 kDa

Gen-ID: 10435

NCBI Accession: NP_006770

UniProt: O14613

Pathways: Regulation of Actin Filament Polymerization