CDC42EP2 Antikörper (C-Term)

Produktnummer ABIN1536701

Produktdetails anti-CDC42EP2 Antikörper

Target: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Bindungsspezifität: AA 133-160, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC42EP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDC42EP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the C-terminal region of human CDC42EP2.

Klon: RB37300

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CDC42EP2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu CDC42EP2

Target: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Andere Bezeichnung: CDC42EP2 (CDC42EP2 Produkte)

Synonyme: CDC42EP2 antikoerper, zgc:103557 antikoerper, BORG1 antikoerper, CEP2 antikoerper, 1110008C05Rik antikoerper, Borg1 antikoerper, Cep2 antikoerper, D19Bwg1013e antikoerper, CDC42 effector protein 2 antikoerper, CDC42 effector protein 2 S homeolog antikoerper, CDC42 effector protein (Rho GTPase binding) 2 antikoerper, CDC42EP2 antikoerper, cdc42ep2.S antikoerper, cdc42ep2 antikoerper, Cdc42ep2 antikoerper

Hintergrund: CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.

Molekulargewicht: 22484

Gen-ID: 10435

NCBI Accession: NP_006770

UniProt: O14613

Pathways: Regulation of Actin Filament Polymerization