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TRKB Antikörper
NTRK2
Reaktivität: Human, Ratte, Maus
IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-TRKB Antikörper
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Target
Alle TRKB (NTRK2) Antikörper anzeigen
TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Reaktivität
Alle Reaktivitäten für TRKB Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für TRKB Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TRKB Antikörper
Polyklonal
Konjugat
Alle Konjugate für TRKB Antikörper
Dieser TRKB Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TRKB Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects endogenous levels of Trk B protein. (region surrounding Asp699)
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography
Reinheit
> 95 % by SDS-PAGE
Top Product
Discover our top product NTRK2 Primärantikörper
Alternativen
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 57-70), (Extracellular Domain) antibody
NTRK2
Reaktivität: Human, Ratte, Maus
WB, IHC, IF, FACS, ICC, LCI
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu TRKB
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Target
TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Andere Bezeichnung
TrkB (NTRK2 Produkte )
Synonyme
trkb antikoerper, trkb-b antikoerper, xtrkb antikoerper, si:ch211-220b11.1 antikoerper, trkB2 antikoerper, NTRK2 antikoerper, ntrk2 antikoerper, gp145-trkb antikoerper, TRKB antikoerper, GP145-TrkB antikoerper, trk-B antikoerper, AI848316 antikoerper, C030027L06Rik antikoerper, Tkrb antikoerper, trkB antikoerper, RATTRKB1 antikoerper, TRKB1 antikoerper, Trk-B antikoerper, TrkB antikoerper, neurotrophic receptor tyrosine kinase 2 antikoerper, neurotrophic receptor tyrosine kinase 2 L homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2b antikoerper, neurotrophic receptor tyrosine kinase 2 S homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2 antikoerper, NTRK2 antikoerper, ntrk2.L antikoerper, ntrk2b antikoerper, ntrk2.S antikoerper, ntrk2 antikoerper, Ntrk2 antikoerper
Hintergrund
The Trk proto-oncogene encodes a tyrosine protein kinase, Trk A, also designated Trk gp140, that serves as a receptor for certain neurotrophic factors including nerve growth factor (NGF) and neurotrophin-3 (NT-3). Trk B is a tyrosine kinase gene highly related to Trk A. Trk B expression is confined to tissues within the central and peripheral nervous systems. The brain-derived neurotrophic factor (BDNF) and NT-3, but not NGF, can induce rapid phosphorylation on tyrosine of Trk B gp145, one of the receptors encoded by Trk B, although BDNF elicits a response at least two orders of magnitude greater than NT-3. Thus it appears that Trk B gp145 may represent a neurotrophic receptor for BDNF and NT-3. The third member of the Trk family of tyrosine kinases, Trk C, encodes a protein designated Trk C gp145 that is preferentially expressed in brain tissue, is equally related to Trk A and Trk B, and is a functional receptor for NT-3.Synonyms: BDNF/NT-3 growth factors receptor, GP145-TrkB, NTRK2, Neurotrophic tyrosine kinase receptor type 2, TRKB, TrkB tyrosine kinase
Molekulargewicht
approx. 92, 145 kDa
Gen-ID
4915
NCBI Accession
NP_001007098
UniProt
Q16620
Pathways
RTK Signalweg , Neurotrophin Signalübertragung , cAMP Metabolic Process , Skeletal Muscle Fiber Development , Feeding Behaviour , Dicarboxylic Acid Transport
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