BUB3 Antikörper

Produktnummer ABIN498373

Produktdetails anti-BUB3 Antikörper

Target: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BUB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Bub3 protein. (region surrounding His274)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BUB3

Target: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Andere Bezeichnung: BUB3 (BUB3 Produkte)

Synonyme: BUB3L antikoerper, hBUB3 antikoerper, Aa2-050 antikoerper, xbub3 antikoerper, AU019800 antikoerper, AU021329 antikoerper, AU043350 antikoerper, AW146323 antikoerper, C78067 antikoerper, BUB3, mitotic checkpoint protein antikoerper, BUB3 mitotic checkpoint protein antikoerper, BUB3 mitotic checkpoint protein L homeolog antikoerper, BUB3 antikoerper, Bub3 antikoerper, bub3.L antikoerper

Hintergrund: The mitotic checkpoint protein Bub3 appears to be essential during normal mitotic progression, preventing premature sister chromatid separation, missegreation and aneuploidy. Bub3 is also important during G2 and early mitosis stages, promoting normal mitotic entry. Loss of Bub3 function causes slower progression through prophase, apparently due to mitotic cyclins A and B not being accumulated.Synonyms: Mitotic checkpoint protein BUB3

Molekulargewicht: approx. 40 kDa

Gen-ID: 9184

NCBI Accession: NP_001007794

UniProt: O43684

Pathways: Maintenance of Protein Location