TSG101 Antikörper
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- Target Alle TSG101 Antikörper anzeigen
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TSG101 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of Tsg 101 protein. (region surrounding Glu303)
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- Affinity chromatography
- Reinheit
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product TSG101 Primärantikörper
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- Applikationshinweise
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
- Andere Bezeichnung
- TSG101 (TSG101 Produkte)
- Synonyme
- CG9712 antikoerper, DmTSG101 antikoerper, Dmel\\CG9712 antikoerper, ESCRT-I antikoerper, Tsg101 antikoerper, burs antikoerper, dTSg101 antikoerper, dTsg101 antikoerper, dVps23 antikoerper, ept antikoerper, tsg101 antikoerper, vps23 antikoerper, TSG101 antikoerper, MGC76193 antikoerper, TSG10 antikoerper, VPS23 antikoerper, AI255943 antikoerper, CC2 antikoerper, Rw antikoerper, zgc:86926 antikoerper, tumor susceptibility 101 antikoerper, Tumor susceptibility gene 101 antikoerper, Tumor Susceptibility Gene homolog antikoerper, tumor susceptibility gene 101 antikoerper, tumor susceptibility 101a antikoerper, tumor susceptibility 101 L homeolog antikoerper, TSG101 antikoerper, tsg-101 antikoerper, tsg101 antikoerper, Tsg101 antikoerper, tsg101a antikoerper, tsg101.L antikoerper
- Hintergrund
- It is now well accepted that the transformation of a normal cell to one that is malignant can result from mutations in genes that encode proteins with key regulatory functions. Examples include the retinoblastoma gene product (Rb p110), p53, VHL and APC. Using a novel cloning strategy that allows the isolation of previously uncharacterized genes encoding selectable recessive phenotypes, an additional tumor suppressor gene has been identified. This gene, termed tsg 101 for tumor susceptibility gene 101, encodes a stathmin binding domain protein. When expression of this growth inhibitory gene is blocked in NIH/3T3 cells using antisense mRNA, the cells exhibit a transformed phenotype and are tumorigenic in SL6 mice.Synonyms: ESCRT-I complex subunit TSG101, Tumor susceptibility gene 101 protein
- Molekulargewicht
- approx. 45 kDa
- Gen-ID
- 7251
- NCBI Accession
- NP_006283
- UniProt
- Q99816
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