TSG101 Antikörper (Middle Region)

Produktnummer ABIN2780037

Produktdetails anti-TSG101 Antikörper

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Ziege, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSG101 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RSELLELIQI MIVIFGEEPP VFSRPTVSAS YPPYTATGPP NTSYMPGMPS

Homologie: Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 93%, Horse: 79%, Human: 79%, Mouse: 100%, Rabbit: 79%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TSG101. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 391 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TSG101 Antikörper (ABIN2780037)

Bychkov, Kirichenko, Mikhaylova, Paramonov, Yastremsky, Kirpichnikov, Shulepko, Lyukmanova: "Extracellular Vesicles Derived from Acidified Metastatic Melanoma Cells Stimulate Growth, Migration, and Stemness of Normal Keratinocytes." in: , Vol. 10, Issue 3, (2022) (PubMed).

Bychkov, Kirichenko, Mikhaylova, Paramonov, Kirpichnikov, Shulepko, Lyukmanova: "Extracellular Vesicles Derived from Metastatic Melanoma Cells Transfer α7-nAChR mRNA, Thus Increasing the Surface Expression of the Receptor and Stimulating the Growth of Normal Keratinocytes." in: Acta naturae, Vol. 14, Issue 3, pp. 95-99, (2022) (PubMed).

Keysberg, Hertel, Schelletter, Busche, Sochart, Kalinowski, Hoffrogge, Otte, Noll: "Exploring the molecular content of CHO exosomes during bioprocessing." in: Applied microbiology and biotechnology, Vol. 105, Issue 9, pp. 3673-3689, (2021) (PubMed).

Leblanc, Arellano-Anaya, Bernard, Gallay, Provansal, Lehmann, Schaeffer, Raposo, Vilette: "Isolation of Exosomes and Microvesicles from Cell Culture Systems to Study Prion Transmission." in: Methods in molecular biology (Clifton, N.J.), Vol. 1545, pp. 153-176, (2016) (PubMed).

Stefan, Claiborn, Stasiek, Chai, Ohta, Longnecker, Greally, Nicholls: "Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes." in: BMC genomics, Vol. 6, pp. 157, (2005) (PubMed).

Details zu TSG101

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Andere Bezeichnung: TSG101 (TSG101 Produkte)

Synonyme: CG9712 antikoerper, DmTSG101 antikoerper, Dmel\\CG9712 antikoerper, ESCRT-I antikoerper, Tsg101 antikoerper, burs antikoerper, dTSg101 antikoerper, dTsg101 antikoerper, dVps23 antikoerper, ept antikoerper, tsg101 antikoerper, vps23 antikoerper, TSG101 antikoerper, MGC76193 antikoerper, TSG10 antikoerper, VPS23 antikoerper, AI255943 antikoerper, CC2 antikoerper, Rw antikoerper, zgc:86926 antikoerper, tumor susceptibility 101 antikoerper, Tumor susceptibility gene 101 antikoerper, Tumor Susceptibility Gene homolog antikoerper, tumor susceptibility gene 101 antikoerper, tumor susceptibility 101a antikoerper, tumor susceptibility 101 L homeolog antikoerper, TSG101 antikoerper, tsg-101 antikoerper, tsg101 antikoerper, Tsg101 antikoerper, tsg101a antikoerper, tsg101.L antikoerper

Hintergrund: TSG101 has a direct role in the control of growth and differentiation in primary epithelial cells. It is required for normal cell function of embryonic and adult tissues but that this gene is not a tumor suppressor for sporadic forms of breast cancer.
Alias Symbols: CC2, AI255943
Protein Interaction Partner: Nr3c2, Ndfip1, SH3KBP1, Ppp1cc, Gjd3, Gjb3, Gjc1, Gja1, Ubc, Mgrn1, Tsg101, Nfe2, Ikbkg, Gmcl1,
Protein Size: 391

Molekulargewicht: 43 kDa

Gen-ID: 22088

NCBI Accession: NM_021884, NP_068684

UniProt: Q61187