SSB Antikörper
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- Target Alle SSB Antikörper anzeigen
- SSB (Sjogren Syndrome Antigen B (SSB))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SSB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of SSB protein.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Affinity chromatography using epitope-specific immunogen
- Reinheit
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product SSB Primärantikörper
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- Applikationshinweise
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- SSB (Sjogren Syndrome Antigen B (SSB))
- Andere Bezeichnung
- SS-B / La (SSB Produkte)
- Synonyme
- LARP3 antikoerper, La antikoerper, lab1 antikoerper, larp3 antikoerper, ssb antikoerper, Mt-SSB antikoerper, MtSSB antikoerper, Ssbp1 antikoerper, SS-B antikoerper, laa-a antikoerper, ssb-a antikoerper, ssb-b antikoerper, wu:fb17f11 antikoerper, zgc:55588 antikoerper, Sjogren syndrome antigen B antikoerper, Sjogren syndrome antigen B L homeolog antikoerper, single stranded DNA binding protein 1 antikoerper, Sjogren syndrome antigen B S homeolog antikoerper, Sjogren syndrome antigen B (autoantigen La) antikoerper, SSB antikoerper, ssb.L antikoerper, SSBP1 antikoerper, Ssb antikoerper, ssb.S antikoerper, ssb antikoerper
- Hintergrund
- Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B and C complex, thereby mediating protein degradation. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. SSB-2 (SplA/ryanodine (SPRY) receptor domain-containing SOCS box protein 2), also known as GGRCC9 (gene-rich cluster protein C9), SPSB2 or MGC2519, is a cytoplasmic protein belonging to the SPSB family of proteins that contain a central SPRY domain and a C-terminal SOCS box. The SPRY domain is believed to be a protein-protein interaction motif. Members of the SPSB family are capable of interacting with Met (a receptor for hepatocyte growth factors (HGFs)), and SSB-1 is known to promote HGF signaling. SSB-1, SSB-2 and SSB-4 are also able to interact with PAR4 (prostate apoptosis response protein 4). Mutations in the genes encoding SPSB proteins are associated with several human diseases.Synonyms: LARP3, La autoantigen, La ribonucleoprotein, Lupus La protein, SSB, Sjoegren syndrome type B antigen
- Molekulargewicht
- approx. 50 kDa
- Gen-ID
- 6741
- NCBI Accession
- NP_003133
- UniProt
- P05455
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