ATP1B1 Antikörper (Internal Region)

Produktnummer ABIN498062

Produktdetails anti-ATP1B1 Antikörper

Target: ATP1B1 (ATPase, Na+/K+ Transporting, beta 1 Polypeptide (ATP1B1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ATP1B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-KTEISFRPND PKSYE

Spezifität: This antibody is expected to recognize both reported isoforms (NP_001668.1, NP_001001787.1).

Kreuzreaktivität (Details): Species reactivity (expected):Human, Canine (Dog), Bovine, Pig.
Species reactivity (tested):Mouse, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the internal region of Human ATP1B1 according to NP_001668.1, NP_001001787.1. Genename: ATP1B1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit: 1/128000. Western blot: 0.1-0.3 μg/mL. Detects a band of Approx 48 kDa in Rat Retina lysates and 58 kDa in Mouse and Rat Kidneylysates. The observed molecular weight corresponds to earlier findings with differentantibodies from other commercial sources.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ATP1B1

Target: ATP1B1 (ATPase, Na+/K+ Transporting, beta 1 Polypeptide (ATP1B1))

Andere Bezeichnung: ATP1B1 (ATP1B1 Produkte)

Synonyme: ATP1B antikoerper, Atp4b antikoerper, Atpb antikoerper, Atpb-1 antikoerper, NKbeta1 antikoerper, ATPBS antikoerper, atp1b1 antikoerper, atp1b1a antikoerper, cb710 antikoerper, ATPase Na+/K+ transporting subunit beta 1 antikoerper, ATPase, Na+/K+ transporting, beta 1 polypeptide antikoerper, ATPase beta chain antikoerper, ATP synthase CF1 beta subunit antikoerper, ATPase Na+/K+ transporting subunit beta 1 S homeolog antikoerper, ATPase, Na+/K+ transporting, beta 1b polypeptide antikoerper, ATP1B1 antikoerper, Atp1b1 antikoerper, atpB antikoerper, atp1b1.S antikoerper, atp1b1b antikoerper

Hintergrund: The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP dependent transport of sodium and potassium across the cell membrane. This membrane bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The enzyme consists of an a and b subunit, both of which exist as isoforms. The a subunit is believed to be the catalytically active subunit, while the b subunit appears necessary for the assembly and transport of the sodium pump to the plasma membrane. The beta subunit is a membrane spanning glycoprotein present in all cell types. The sodium/potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families. The different isoforms of the sodium/potassium ATPase exhibit a tissue-specific and developmental pattern of expression. The alpha 1 and beta mRNAs are present in all cell types examined whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell-specific expression.Synonyms: Sodium Pump ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1, Sodium/potassium-transporting ATPase subunit beta-1

Molekulargewicht: 35.1 kDa (Human NP_001668.1), 35.1 kDa (Mouse NP_033851.1) and 35.1 kDa (Rat NP_037245.2)

Gen-ID: 481

NCBI Accession: NP_001001787

UniProt: P05026

Pathways: Thyroid Hormone Synthesis, Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interaktom