ATP1B1 Antikörper (Middle Region)

Produktnummer ABIN2781852

Produktdetails anti-ATP1B1 Antikörper

Target: ATP1B1 (ATPase, Na+/K+ Transporting, beta 1 Polypeptide (ATP1B1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Schaf, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP1B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VMKYNPNVLP VQCTGKRDED KDKVGNVEYF GLGNSPGFPL QYYPYYGKLL

Homologie: Cow: 92%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 92%, Rat: 100%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ATP1B1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATP1B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 301 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATP1B1

Target: ATP1B1 (ATPase, Na+/K+ Transporting, beta 1 Polypeptide (ATP1B1))

Andere Bezeichnung: ATP1B1 (ATP1B1 Produkte)

Synonyme: ATP1B antikoerper, Atp4b antikoerper, Atpb antikoerper, Atpb-1 antikoerper, NKbeta1 antikoerper, ATPBS antikoerper, atp1b1 antikoerper, atp1b1a antikoerper, cb710 antikoerper, ATPase Na+/K+ transporting subunit beta 1 antikoerper, ATPase, Na+/K+ transporting, beta 1 polypeptide antikoerper, ATPase beta chain antikoerper, ATP synthase CF1 beta subunit antikoerper, ATPase Na+/K+ transporting subunit beta 1 S homeolog antikoerper, ATPase, Na+/K+ transporting, beta 1b polypeptide antikoerper, ATP1B1 antikoerper, Atp1b1 antikoerper, atpB antikoerper, atp1b1.S antikoerper, atp1b1b antikoerper

Hintergrund: ATP1B1 belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit.The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: ATP1B, MGC1798
Protein Interaction Partner: Bace1, EGFR, ATP4A, UBC, BRCA1, BARD1, PAXIP1, GCH1, USP4, NEDD4L, ELAVL1, NDRG2, TRMT2A, DDAH2, HLA-DRB1, HLA-DRA, EZH2, CRIP2, KMT2B, PSME1, HLA-DRB5, HLA-DRB4, HLA-DRB3, LRIF1, FXYD7, FXYD1,
Protein Size: 301

Molekulargewicht: 35 kDa

Gen-ID: 481

NCBI Accession: NM_001001787, NP_001001787

UniProt: P05026

Pathways: Thyroid Hormone Synthesis, Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interaktom