GLP2R Antikörper (Extracellular Domain, N-Term)

Produktnummer ABIN497997

Produktdetails anti-GLP2R Antikörper

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Bindungsspezifität: Extracellular Domain, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLP2R Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with Glucagon-Like Peptide 2 Receptor (GLP2R).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to N-terminal extracellular domain of Human GLP2R. .Remarks: The immunizing peptide shows 81% identity (87% similarity) with Rat.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Formalin Fixed Paraffin Embedded Tissues: 5-10 μg/mL(Requires pretreatment with Proteinase K).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.6 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu GLP2R

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Andere Bezeichnung: GLP2 Receptor (GLP2R Produkte)

Synonyme: 9530092J08Rik antikoerper, GLP-2 antikoerper, glucagon like peptide 2 receptor antikoerper, glucagon-like peptide 2 receptor antikoerper, GLP2R antikoerper, Glp2r antikoerper

Hintergrund: GLP2R, a Glucagon Receptor, is closely related to the Glucagon Receptor and to the GLP1 Receptor. The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides cosecreted from gut endocrine cells in response to nutrient ingestion. The actions of GLP-2 are mediated by the GLP-2 receptor expressed on subsets of enteric nerves and enteroendocrine cells in the stomach and small and large intestine. Activation of GLP2R signaling promotes expansion of the mucosal epithelium indirectly via activation of growth and anti-apoptotic pathways. GLP2R, through its ligand glucagon-like peptide 2 (GLP2), has been shown to prevent intestinal hypoplasia resulting from total parenteral nutrition. GLP2R has been reported primarily in the gastrointestinal tract, including intestine and stomach. In rats, GLPR2 has been shown in brain and lung. An EST has been isolated from a lung cancer library.Synonyms: GLP-2-R, GLP-2R, GLP2R, Glucagon-like peptide 2 receptor

Gen-ID: 9340

NCBI Accession: NP_004237

UniProt: O95838

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour