WNT3 Antikörper (AA 155-184)

Produktnummer ABIN3029628

Produktdetails anti-WNT3 Antikörper

Target: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Bindungsspezifität: AA 155-184

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Chicken, Xenopus

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 155-184 from the human protein was used as the immunogen for this WNT3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the WNT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the WNT3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu WNT3

Target: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Andere Bezeichnung: WNT3 (WNT3 Produkte)

Synonyme: INT4 antikoerper, Ci-Wnt3 antikoerper, WNT3 antikoerper, int4 antikoerper, Xwnt3 antikoerper, wnt-3 antikoerper, wnt3l antikoerper, Xwnt-3 antikoerper, wnt3 antikoerper, Int-4 antikoerper, Wnt-3 antikoerper, wnt3-A antikoerper, Wnt family member 3 antikoerper, wingless-type MMTV integration site family, member 3 antikoerper, proto-oncogene Wnt-3 antikoerper, wingless-type MMTV integration site family member 3 antikoerper, Wnt family member 3A antikoerper, wingless-type MMTV integration site family member 3 L homeolog antikoerper, WNT3 antikoerper, Wnt3 antikoerper, wnt3 antikoerper, LOC468297 antikoerper, WNT3A antikoerper, wnt3.L antikoerper

Hintergrund: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

UniProt: P56703

Pathways: WNT Signalweg, Regulation of Cell Size