CYP1A1 Antikörper (AA 377-405)

Produktnummer ABIN3030669

Produktdetails anti-CYP1A1 Antikörper

Target: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Bindungsspezifität: AA 377-405

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CYP1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Primate

Aufreinigung: Purified

Immunogen: A portion of amino acids 377-405 from the human protein was used as the immunogen for this CYP1A1 antibody.

Klon: 655CT6-1-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Titration of the CYP1A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CYP1A1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CYP1A1

Target: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Andere Bezeichnung: CYP1A1 (CYP1A1 Produkte)

Synonyme: AHH antikoerper, AHRR antikoerper, CP11 antikoerper, CYP1 antikoerper, P1-450 antikoerper, P450-C antikoerper, P450DX antikoerper, Cyp1a2 antikoerper, P450-1 antikoerper, cyp1a1 antikoerper, CYP1A1 antikoerper, CYPIA1 antikoerper, Cyp45c antikoerper, Cypc45c antikoerper, P-450MC antikoerper, wu:fb63b04 antikoerper, zfCYP1A antikoerper, zgc:109747 antikoerper, ahh antikoerper, ahrr antikoerper, cp11 antikoerper, cyp1 antikoerper, cyp1a antikoerper, p1-450 antikoerper, p450-c antikoerper, p450dx antikoerper, cytochrome P450 family 1 subfamily A member 1 antikoerper, cytochrome P450 1A1 antikoerper, cytochrome P450, family 1, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 1, subfamily A, polypeptide 1 antikoerper, cytochrome P450 family 1 subfamily D polypeptide 1 antikoerper, cytochrome P4501A1 antikoerper, polycyclic hydrocarbon-inducible cytochrome P450c antikoerper, cytochrome P450, family 1, subfamily A antikoerper, cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 antikoerper, cytochrome P450 family 1 subfamily A member 1 L homeolog antikoerper, CYP1A1 antikoerper, CpipJ_CPIJ010542 antikoerper, Cyp1a1 antikoerper, cyp1d1 antikoerper, LOC100328613 antikoerper, cyp1a antikoerper, LOC102129994 antikoerper, cyp1a1.L antikoerper

Hintergrund: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

UniProt: P04798

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha