CDKN2C Antikörper (AA 113-139)

Produktnummer ABIN3030649

Produktdetails anti-CDKN2C Antikörper

Target: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Bindungsspezifität: AA 113-139

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKN2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 113-139 from the human protein was used as the immunogen for this CDKN2C antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the CDKN2C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CDKN2C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CDKN2C

Target: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Andere Bezeichnung: CDKN2C (CDKN2C Produkte)

Synonyme: CDKN2C antikoerper, p18 antikoerper, ink4c antikoerper, p18-ink4c antikoerper, INK4C antikoerper, p18-INK4C antikoerper, C77269 antikoerper, INK4c antikoerper, INK4d antikoerper, p18INK4c antikoerper, cyclin dependent kinase inhibitor 2C antikoerper, cyclin-dependent kinase inhibitor 2C antikoerper, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) antikoerper, CDKN2C antikoerper, cdkn2c antikoerper, Cdkn2c antikoerper

Hintergrund: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.

UniProt: P42773

Pathways: Zellzyklus, Mitotic G1-G1/S Phases