Peroxiredoxin 5 Antikörper (AA 66-198)

Produktnummer ABIN4952126

Produktdetails anti-Peroxiredoxin 5 Antikörper

Target: Peroxiredoxin 5 (PRDX5)

Bindungsspezifität: AA 66-198

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Amino acids 66-198 of human Peroxiredoxin 5 were used as the immunogen for the Peroxiredoxin 5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Peroxiredoxin 5 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,Immunocytochemistry: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Peroxiredoxin 5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Peroxiredoxin 5

Target: Peroxiredoxin 5 (PRDX5)

Andere Bezeichnung: Peroxiredoxin 5 (PRDX5 Produkte)

Synonyme: acr1 antikoerper, aoeb166 antikoerper, pmp20 antikoerper, prx-5 antikoerper, prx5 antikoerper, prxv antikoerper, sbbi10 antikoerper, GB16965 antikoerper, zgc:112318 antikoerper, PRDX5 antikoerper, CG 32920 antikoerper, CG 7217 antikoerper, CG32920 antikoerper, CG7217 antikoerper, Dmel\\CG7217 antikoerper, dPrx5 antikoerper, dprx5 antikoerper, ACR1 antikoerper, AOEB166 antikoerper, B166 antikoerper, PLP antikoerper, PMP20 antikoerper, PRDX6 antikoerper, PRXV antikoerper, prx-V antikoerper, AOPP antikoerper, Pmp20 antikoerper, Prdx6 antikoerper, PrxV antikoerper, Aoeb166 antikoerper, Prx V antikoerper, peroxiredoxin 5 L homeolog antikoerper, peroxiredoxin-5, mitochondrial antikoerper, peroxiredoxin 5 antikoerper, Peroxiredoxin 5 antikoerper, prdx5.L antikoerper, LOC552429 antikoerper, prdx5 antikoerper, PRDX5 antikoerper, Prx5 antikoerper, Prdx5 antikoerper

Hintergrund: PRDX5 (Peroxiredoxin 5) also known as PMP20, PRDX6, PRXV, SBBI10, is a member of the peroxiredoxin family and may play an antioxidant protective role in various tissues under nonpathologic conditions and during inflammatory processes. The PRDX5 gene is mapped to11q13.1. PRDX5 displays mitochondrial presequence features and has 3 cysteines implicated in antioxidant activity and a C-terminal SQL peroxisomal targeting sequence. Northern blot analysis revealed ubiquitous expression of a 1.0-kb PRDX5 transcript in tissues and cell lines. Functional analysis showed that PRDX5 has antioxidant activity equivalent to that of CAT. While PRDX5 was localized to fibroblasts in normal tendon, it was localized to fibroblasts and endothelial cells in degenerative tendon. PRDX5 mRNA and protein levels increased at 12 hours, and the increase in PRDX5 expression correlated with reduced peroxide levels. PRDX5 plays a protective role against oxidative stress in human cartilage.

UniProt: P30044

Pathways: Cell RedoxHomeostasis