KCNA5 Antikörper

Produktnummer ABIN4951521

Produktdetails anti-KCNA5 Antikörper

Target: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids LEKCNVKAKSNVDLRRSLYALCLDTSRETDL of human KCNA5 were used as the immunogen for the KCNA5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the KCNA5 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the KCNA5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu KCNA5

Target: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Andere Bezeichnung: KCNA5 / Kv1.5 (KCNA5 Produkte)

Synonyme: KCNA5 antikoerper, kcna5 antikoerper, ATFB7 antikoerper, HCK1 antikoerper, HK2 antikoerper, HPCN1 antikoerper, KV1.5 antikoerper, PCN1 antikoerper, Kv1.5 antikoerper, Kv1 antikoerper, potassium voltage-gated channel subfamily A member 5 antikoerper, potassium channel, voltage gated shaker related subfamily A, member 5 antikoerper, potassium voltage-gated channel, shaker-related subfamily, member 5 antikoerper, KCNA5 antikoerper, kcna5 antikoerper, Kcna5 antikoerper

Hintergrund: Potassium voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene. Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization, thereby contributing to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Mutations in this gene have been related to both atrial fibrillation and sudden cardiac death. KCNA5 are also key players in pulmonary vascular function, where they play a role in setting the resting membrane potential and its involvement during hypoxic pulmonary vasoconstriction.

UniProt: P22460