COPS5 Antikörper (AA 8-334)

Produktnummer ABIN4951504

Produktdetails anti-COPS5 Antikörper

Target: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Bindungsspezifität: AA 8-334

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPS5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Amino acids 8-334 of human JAB1 were used as the immunogen for the JAB1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the JAB1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the JAB1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu COPS5

Target: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Andere Bezeichnung: JAB1 (COPS5 Produkte)

Synonyme: BcDNA.LD14392 antikoerper, BcDNA:LD14392 antikoerper, CG14884 antikoerper, CH5 antikoerper, CSN-5 antikoerper, Csn5 antikoerper, DCH5 antikoerper, Dch5 antikoerper, Dmel\\CG14884 antikoerper, JAB1 antikoerper, JAB1/CSN5 antikoerper, Jab1 antikoerper, JadBp antikoerper, csn5 antikoerper, dch5 antikoerper, jab1/csn5 antikoerper, l(3)89Cf antikoerper, l(3)L4032 antikoerper, l(3)M203 antikoerper, quo antikoerper, COPS5 antikoerper, MGC76063 antikoerper, AI303502 antikoerper, CSN5 antikoerper, Mov34 antikoerper, Sgn5 antikoerper, zgc:73130 antikoerper, MOV-34 antikoerper, SGN5 antikoerper, COP9 signalosome subunit 5 antikoerper, COP9 signalosome complex subunit 5 antikoerper, COP9 signalosome subunit 5 S homeolog antikoerper, CSN5 antikoerper, COPS5 antikoerper, cops5 antikoerper, CpipJ_CPIJ012314 antikoerper, Bm1_46585 antikoerper, VDBG_06932 antikoerper, LOAG_01443 antikoerper, csn5 antikoerper, Cops5 antikoerper, cops5.S antikoerper, csn-5 antikoerper

Hintergrund: COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or JAB1, is a gene conserved from humans to Saccharomyces cerevisiae. It is a member of the MOV34 family. COPS5 is mapped to 8q13.1. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. COPS5 can interact with the cytoplasmic domain of the beta-2 subunit of the alpha-L/beta-2 integrin LFA1, and it is the only protein demonstrated to interact with MIF. COPS5, VHL, and TRC8 proteins appear to be linked both physically and functionally, and all 3 may participate in the development of kidney cancer. In addition to that, COPS5 is an essential cofactor for the apoptotic function of E2F1.

UniProt: Q92905

Pathways: Zellzyklus