FXYD1 Antikörper (AA 21-92)

Produktnummer ABIN4951107

Produktdetails anti-FXYD1 Antikörper

Target: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Bindungsspezifität: AA 21-92

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FXYD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Amino acids 21-92 of human FXYD1 were used as the immunogen for the FXYD1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the FXYD1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the FXYD1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu FXYD1

Target: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Andere Bezeichnung: FXYD1 (FXYD1 Produkte)

Synonyme: PLM antikoerper, 0610012C17Rik antikoerper, 1110006M24Rik antikoerper, Plm antikoerper, Pml antikoerper, FXYD domain containing ion transport regulator 1 antikoerper, FXYD domain-containing ion transport regulator 1 antikoerper, FXYD1 antikoerper, Fxyd1 antikoerper

Hintergrund: Phospholemman is a protein that in humans is encoded by the FXYD1 gene. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. Transcript variants with different 5' UTR sequences have been described in the literature.

UniProt: O00168