WRNIP1 Antikörper

Produktnummer ABIN4905632

Produktdetails anti-WRNIP1 Antikörper

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WRNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene.

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human WRNIP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu WRNIP1

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Andere Bezeichnung: WRNIP1 (WRNIP1 Produkte)

Synonyme: WRNIP1 antikoerper, wrnip1 antikoerper, RP11-420G6.2 antikoerper, WHIP antikoerper, bA420G6.2 antikoerper, zgc:85976 antikoerper, 4833444L21Rik antikoerper, Wrnip antikoerper, Whip antikoerper, Werner helicase interacting protein 1 antikoerper, Werner helicase interacting protein 1 L homeolog antikoerper, ATPase WRNIP1 antikoerper, WRNIP1 antikoerper, wrnip1.L antikoerper, wrnip1 antikoerper, EDI_075920 antikoerper, CpipJ_CPIJ017857 antikoerper, PITG_07216 antikoerper, VDBG_02914 antikoerper, Wrnip1 antikoerper, PGTG_08805 antikoerper

Gen-ID: 56897

UniProt: Q96S55