INCENP Antikörper

Produktnummer ABIN4904057

Produktdetails anti-INCENP Antikörper

Target: INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INCENP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A, MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143), MCAK (MIM 604538), KID (MIM 603213), cytoplasmic dynein (e.g., MIM 600112), CliPs (e.g., MIM 179838), and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human INCENP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu INCENP

Target: INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))

Andere Bezeichnung: INCENP (INCENP Produkte)

Synonyme: INCENP antikoerper, LOC572121 antikoerper, 2700067E22Rik antikoerper, AU019509 antikoerper, C130081E20 antikoerper, C77457 antikoerper, XL-INCENP antikoerper, incenp antikoerper, incenp-a antikoerper, incenp-b antikoerper, xINC antikoerper, xIncenp antikoerper, xl-incenp antikoerper, inner centromere protein antikoerper, inner centromere protein S homeolog antikoerper, inner centromere protein L homeolog antikoerper, INCENP antikoerper, Incenp antikoerper, incenp.S antikoerper, incenp antikoerper, incenp.L antikoerper

Gen-ID: 3619

UniProt: Q9NQS7

Pathways: Zellzyklus