MAP1LC3A Antikörper
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- Target Alle MAP1LC3A Antikörper anzeigen
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MAP1LC3A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- LC3A is a protein encoded by the MAP1LC3A gene which is approximately 14,3 kD. LC3A is localised to the cytoplasm, cytoskeleton and autophagosome. It is involved in pathways such as the autophagy pathway, pink/parkin mediated mitophagy, ferroptosis, cellular senescence and pathways affecting insulin-like growth factor-Akt signalling. MAP1A and MAP1B fall under the LC3A protein. They are microtubule-associated proteins that mediate the physical interactions between microtubules and components of the cytoskeleton. LC3A is most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. Mutations in the LC3A gene may result in Nasu-Hakola disease , lacrimal gland adenocarcinoma and leber congenital amaurosis. STJ97755 was developed from clone 5G10. It was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous levels of LC3A.
- Spezifität
- LC3A Mouse Monoclonal Antibody (5G10) detects endogenous levels of LC3A
- Produktmerkmale
- Mouse Monoclonal to LC3A.
- Aufreinigung
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Immunogen
- synthetic peptide derived from LC3A
- Klon
- 5G10
- Isotyp
- IgG1
- Top Product
- Discover our top product MAP1LC3A Primärantikörper
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- Applikationshinweise
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WB 1:1000-2000
IHC 1:100-200 - Kommentare
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Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
- Andere Bezeichnung
- LC3A (MAP1LC3A Produkte)
- Synonyme
- ATG8E antikoerper, LC3 antikoerper, LC3A antikoerper, MAP1ALC3 antikoerper, MAP1BLC3 antikoerper, 1010001H21Rik antikoerper, 4922501H04Rik antikoerper, LC3a antikoerper, MGC69006 antikoerper, zgc:77094 antikoerper, MGC89867 antikoerper, MAP1LC3A antikoerper, map1lc3a antikoerper, microtubule associated protein 1 light chain 3 alpha antikoerper, microtubule-associated protein 1 light chain 3 alpha antikoerper, microtubule associated protein 1 light chain 3 alpha S homeolog antikoerper, MAP1LC3A antikoerper, Map1lc3a antikoerper, map1lc3a.S antikoerper, map1lc3a antikoerper
- Gen-ID
- 84557
- UniProt
- Q9H492
- Pathways
- Autophagie
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