ALIX Antikörper

Produktnummer ABIN4915785

Produktdetails anti-ALIX Antikörper

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ALIX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: Reacts with human ALIX protein

Aufreinigung: Purified (protein A)

Immunogen: Purified recombinant human ALIX protein

Klon: 8E8

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB(1:200 - 1:1000) IHC(1:100 - 1:500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Konzentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu ALIX

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Andere Bezeichnung: ALIX (PDCD6IP Produkte)

Synonyme: DDBDRAFT_0167145 antikoerper, DDBDRAFT_0185177 antikoerper, DDB_0167145 antikoerper, DDB_0185177 antikoerper, AIP1 antikoerper, ALIX antikoerper, DRIP4 antikoerper, HP95 antikoerper, AI480591 antikoerper, AW544830 antikoerper, Aip1 antikoerper, Alix antikoerper, C76364 antikoerper, Eig2 antikoerper, mKIAA1375 antikoerper, CG12876 antikoerper, DAIP1 antikoerper, Dmel\\CG12876 antikoerper, GB11744 antikoerper, RGD1561176 antikoerper, zgc:63638 antikoerper, wu:fb70d03 antikoerper, wu:fy65h02 antikoerper, PDCD6IP antikoerper, aip1 antikoerper, alix antikoerper, hp95 antikoerper, drip4 antikoerper, ALG-2 interacting protein X antikoerper, programmed cell death 6 interacting protein antikoerper, programmed cell death 6-interacting protein antikoerper, Programmed cell death 6 interacting protein antikoerper, programmed cell death 6 interacting protein L homeolog antikoerper, alxA antikoerper, PDCD6IP antikoerper, Pdcd6ip antikoerper, ALiX antikoerper, LOC412662 antikoerper, pdcd6ip antikoerper, Bm1_48390 antikoerper, pdcd6ip.L antikoerper

Hintergrund: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).

Gen-ID: 10015

UniProt: Q8WUM4

Pathways: p53 Signalweg, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation