ALIX Antikörper (AA 601-700)

Produktnummer ABIN873235

Produktdetails anti-ALIX Antikörper

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Bindungsspezifität: AA 601-700

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALIX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDC6I

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ALIX

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Andere Bezeichnung: PDC6I (PDCD6IP Produkte)

Synonyme: DDBDRAFT_0167145 antikoerper, DDBDRAFT_0185177 antikoerper, DDB_0167145 antikoerper, DDB_0185177 antikoerper, AIP1 antikoerper, ALIX antikoerper, DRIP4 antikoerper, HP95 antikoerper, AI480591 antikoerper, AW544830 antikoerper, Aip1 antikoerper, Alix antikoerper, C76364 antikoerper, Eig2 antikoerper, mKIAA1375 antikoerper, CG12876 antikoerper, DAIP1 antikoerper, Dmel\\CG12876 antikoerper, GB11744 antikoerper, RGD1561176 antikoerper, zgc:63638 antikoerper, wu:fb70d03 antikoerper, wu:fy65h02 antikoerper, PDCD6IP antikoerper, aip1 antikoerper, alix antikoerper, hp95 antikoerper, drip4 antikoerper, ALG-2 interacting protein X antikoerper, programmed cell death 6 interacting protein antikoerper, programmed cell death 6-interacting protein antikoerper, Programmed cell death 6 interacting protein antikoerper, programmed cell death 6 interacting protein L homeolog antikoerper, alxA antikoerper, PDCD6IP antikoerper, Pdcd6ip antikoerper, ALiX antikoerper, LOC412662 antikoerper, pdcd6ip antikoerper, Bm1_48390 antikoerper, pdcd6ip.L antikoerper

Hintergrund:

Synonyms: AIP1, ALG 2 interacting protein 1, ALG-2-interacting protein 1, ALG2 interacting protein X, Alix, Apoptosis linked gene 2 interacting protein X, Dopamine receptor interacting protein 4, DRIP4, HP95, KIAA1375, MGC17003, PDC6I_HUMAN, PDCD6 interacting protein, PDCD6-interacting protein, PDCD6IP, Programmed cell death 6 interacting protein, Programmed cell death 6-interacting protein.

Background: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release, this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.

Gen-ID: 10015

Pathways: p53 Signalweg, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation