KCNJ11 Antikörper (AA 18-30)

Produktnummer ABIN461944

Produktdetails anti-KCNJ11 Antikörper

Target: KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))

Bindungsspezifität: AA 18-30

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser KCNJ11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human KCNJ11 / Kir6.2. This antibody is expected to recognise isoform 1 (NP_000516.3) only.

Homologie: Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Monkey (85%), Bovine (85%), Dog (85%), Bat (85%), Horse (85%), Rabbit (85%), Platypus (85%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-AEDPAKPRYRARQ from an internal region (near the N-terminus) of human KCNJ11 / Kir6.2 (NP_000516.3). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Monkey (85%), Bovine (85%), Dog (85%), Bat (85%), Horse (85%), Rabbit (85%), Platypus (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000), WB (0.1 - 0.3 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu KCNJ11

Target: KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))

Andere Bezeichnung: KCNJ11 / Kir6.2 (KCNJ11 Produkte)

Synonyme: kir6.2 antikoerper, Kir6.2 antikoerper, mBIR antikoerper, BIR antikoerper, HHF2 antikoerper, IKATP antikoerper, KIR6.2 antikoerper, PHHI antikoerper, TNDM3 antikoerper, potassium voltage-gated channel subfamily J member 11 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 11 antikoerper, potassium inwardly rectifying channel, subfamily J, member 11 antikoerper, KCNJ11 antikoerper, kcnj11 antikoerper, Kcnj11 antikoerper

Hintergrund: Name/Gene ID: KCNJ11
Subfamily: Potassium channel - inward-rectifying
Family: Ion Channel

Synonyms: KCNJ11, BIR, IKATP, HHF2, PHHI, TNDM3, Beta-cell KATP channel, KIR6.2

Gen-ID: 3767

NCBI Accession: NP_000516

UniProt: Q14654

Pathways: Negative Regulation of Hormone Secretion