EIF4B Antikörper (AA 420-424)

Produktnummer ABIN401568

Produktdetails anti-EIF4B Antikörper

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Bindungsspezifität: AA 420-424

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of total eIF4B protein.

Aufreinigung: Immunoaffinity Chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around amino acids 420~424 (T-G-S-E-S) derived from Human eIF4B.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500approx. 1/1000. Incubate membrane with diluted antibody in 5 % nonfat milk, 1X TBS, 0.1 % Tween-20 at 4 °Cwith gentle shaking, overnight. Immunohistochemistry on Paraffin Sections: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at-20 °C.

Details zu EIF4B

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Andere Bezeichnung: EIF4B (EIF4B Produkte)

Synonyme: EIF-4B antikoerper, PRO1843 antikoerper, CG10837 antikoerper, Dm-eIF4B antikoerper, Dmel\\CG10837 antikoerper, Eif4B antikoerper, eIF-4B-L antikoerper, eIF-4B-S antikoerper, eIF-4b antikoerper, eIF4B antikoerper, eIF4B-L antikoerper, eIF4B-S antikoerper, eIf4b antikoerper, 2310046H11Rik antikoerper, AL024095 antikoerper, C85189 antikoerper, Eif4a2 antikoerper, eif4b antikoerper, fb15c09 antikoerper, wu:fb15c09 antikoerper, zgc:101532 antikoerper, MGC89384 antikoerper, eukaryotic translation initiation factor 4B antikoerper, eukaryotic initiation factor 4B antikoerper, Eukaryotic initiation factor 4B antikoerper, eukaryotic translation initiation factor 4Bb antikoerper, eukaryotic translation initiation factor 4Ba antikoerper, eukaryotic translation initiation factor 4B S homeolog antikoerper, EIF4B antikoerper, Eif4B antikoerper, eIF-4B antikoerper, Eif4b antikoerper, eif4bb antikoerper, eif4b antikoerper, eif4ba antikoerper, eif4b.S antikoerper, LOC100284982 antikoerper, LOC100380867 antikoerper

Hintergrund: EIF4B is required for the binding of mRNA to ribosomes. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F (referenced from swissprot).Synonyms: Eukaryotic translation initiation factor 4B, eIF-4B

Gen-ID: 1975

NCBI Accession: NP_001408

UniProt: P23588