EIF4B Antikörper (C-Term)
Kurzübersicht für EIF4B Antikörper (C-Term) (ABIN2778771)
Target
Alle EIF4B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- EIF4B Antibody - C-terminal region
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Sequenz
- NPPARSQSSD TEQQSPTSGG GKVAPAQPSE EGPGRKDENK VDGMNAPKGQ
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Homologie
- Cow: 79%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against EIF4B. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4B
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099976
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).
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- EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))
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Andere Bezeichnung
- EIF4B
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Hintergrund
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Background Information: IF4B contains 1 RRM (RNA recognition motif) domain and is required for the binding of mRNA to ribosomes. Functions of EIF4B are in close association with EEF4-F and EIF4-A. It binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP and promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Gene Name: Eukaryotic translation initiation factor 4B
Alternative Symbols: EIF-4B, PRO1843
Protein Name: Eukaryotic translation initiation factor 4B
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Molekulargewicht
- 67kDa
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Gen-ID
- 1975
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NCBI Accession
- NP_001408
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UniProt
- P23588
Target
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