ABCB6 Antikörper (AA 440-455)

Produktnummer ABIN401357

Produktdetails anti-ABCB6 Antikörper

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Bindungsspezifität: AA 440-455

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody is directed against ABCB6 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding to amino acids 440-455 of human ABCB6 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/40,000 - 1/200,000. Western Blot: 1/1,000 - 1/5,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu ABCB6

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Andere Bezeichnung: ABCB6 (ABCB6 Produkte)

Synonyme: ABCB6 antikoerper, abcb6 antikoerper, ABC antikoerper, ABC14 antikoerper, LAN antikoerper, MCOPCB7 antikoerper, MTABC3 antikoerper, PRP antikoerper, umat antikoerper, 1200005B17Rik antikoerper, ATP binding cassette subfamily B member 6 (Langereis blood group) antikoerper, ATP binding cassette subfamily B member 6 antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 6a antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 6 antikoerper, ABCB6 antikoerper, abcb6a antikoerper, abcb6 antikoerper, Abcb6 antikoerper

Hintergrund: ABCB6 (ATP-binding cassette sub-family B member 6, also known as mitochondrial precursor ABC transporter 3, Mt-ABC transporter 3, and ABC transporter umat) is a member of the superfamily of ATPbinding cassette (ABC) transporters. ABCB6 is a membrane-associated protein that transports various molecules across the extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, DR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily confer multi-drug resistance (MDR) to cancer cells and are also involved in antigen presentation. ABCB6 also likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.Synonyms: ATP-binding cassette sub-family B member 6 mitochondrial, MTABC3, Mitochondrial ABC transporter 3, P-glycoprotein-related protein, PRP, UMAT, Ubiquitously-expressed mammalian ABC half transporter

Gen-ID: 10058

NCBI Accession: NP_005680

UniProt: Q9NP58

Pathways: Transition Metal Ion Homeostasis